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Red Willow County is a county located in the U.S. state of Nebraska. Its county seat is McCook.  In the Nebraska license plate system, Red Willow County is represented by the prefix 48.

• Area: 718 square miles
• Founded: 1879
• Population (2021): 10,623
• County Seat: McCook
• Cities: McCook, Indianola, Bartley, Danbury, Lebanon
• Rivers: Medicine Creek, Red Willow Creek, Driftwood Creek, Republican River